Intended for healthcare professionals

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Clinical Review State of the Art Review

The role of the gut microbiome in systemic inflammatory disease

BMJ 2018; 360 doi: (Published 08 January 2018) Cite this as: BMJ 2018;360:j5145

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Relationship between microbiota and multiple sclerosis as an autoimmune inflammatory disease

According to recent studies, there is evidence that dysbiosis in the microbiota of patients with multiple sclerosis may favor inflammatory activation processes, additionally it has been proven in experimental models of multiple sclerosis that the alteration of the intestinal microbiota affects the activity of the Treg cells which produce a non-tolerogenic inflammation prone environment. These changes may favor the immune response that could participate in the autoimmunity of multiple sclerosis.

Competing interests: No competing interests

09 August 2019
Harold S. Cuaran
Medical student
Surcolombiana University Street 9 # 15-25,