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Antibody drug improves desensitisation with oral immunotherapy in children with multifood allergy, study finds

BMJ 2017; 359 doi: (Published 12 December 2017) Cite this as: BMJ 2017;359:j5736
  1. Susan Mayor
  1. London

Pretreatment with the anti-immunoglobulin E (IgE) antibody omalizumab improved the efficacy of oral immunotherapy in children with multiple food allergies, results from a small phase 2 trial have shown.1

Around 30% of people with food allergies are allergic to multiple foods. But, although several previous studies have shown improvements with oral immunotherapy in people allergic to single foods, few have investigated multifood allergy.

The new study investigated omalizumab, which reduces blood levels of free IgE, together with oral immunotherapy. This combination was chosen because previous studies have shown the …

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