Research News

Faecal transplant given in oral capsule reduces recurrent C difficile, shows study

BMJ 2017; 359 doi: https://doi.org/10.1136/bmj.j5501 (Published 28 November 2017) Cite this as: BMJ 2017;359:j5501
  1. Susan Mayor
  1. London

Faecal microbiota transplantation delivered orally in a capsule prevents recurrent Clostridium difficile infection in at-risk adults as effectively as transplantation of donor stool material by colonoscopy, a randomised trial has found.1

Infection with C difficile is the leading cause of healthcare associated infectious diarrhoea and recurrent infection is common. Between 10% and 30% of patients have a recurrence and this risk increases to 60% after the third episode.

Faecal microbiota transplantation, which involves giving faecal matter from a healthy donor, …

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