The reason why NSAID is able to treat dysuria (1 ) is most likely because most cases of dysuria is caused by inflammation of the urethra due to soap, not to bacteria. This is what I discovered when I asked 50 women with symptomatic urinary tract infection (UTI), urethral syndrome (dysuria without bacteriuria), or asymptomatic bacturia (ABU) how often they washed their sexual organs with soap. In the two first groups 15/17 and 14/14, respectively used soap, whereas 13/19 among those with ABU used water only (p<0.00001). I told all of them to use water only, and at follow-up dysuria had disappeared in almost all of those who had followed my advice (2).
References
Kronenberg A, Bütikofer L, Odutayo A, et al. Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial. BMJ 2017;359:j4784.
Ravnskov U. Soap is the major cause of dysuria. Lancet 1984;1:1027-8.
Rapid Response:
Dysuria is caused by soap, not by bacteria
The reason why NSAID is able to treat dysuria (1 ) is most likely because most cases of dysuria is caused by inflammation of the urethra due to soap, not to bacteria. This is what I discovered when I asked 50 women with symptomatic urinary tract infection (UTI), urethral syndrome (dysuria without bacteriuria), or asymptomatic bacturia (ABU) how often they washed their sexual organs with soap. In the two first groups 15/17 and 14/14, respectively used soap, whereas 13/19 among those with ABU used water only (p<0.00001). I told all of them to use water only, and at follow-up dysuria had disappeared in almost all of those who had followed my advice (2).
References
Kronenberg A, Bütikofer L, Odutayo A, et al. Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial. BMJ 2017;359:j4784.
Ravnskov U. Soap is the major cause of dysuria. Lancet 1984;1:1027-8.
Competing interests: No competing interests