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PrEP on demand reduces HIV infections, study finds

BMJ 2017; 358 doi: (Published 26 July 2017) Cite this as: BMJ 2017;358:j3619
  1. Sophie Cousins
  1. Paris

On demand pre-exposure prophylaxis (PrEP) to prevent HIV infection is highly effective in men who have infrequent sex with men, shows research presented this week at the International AIDS Society’s Conference on HIV Science in Paris, France.

A sub-study of ANRS IPERGAY, a major trial examining the efficacy of on-demand PrEP, found that participants who took fewer than 15 tablets a month—but took one each time they had sex—showed no new HIV infections, compared with six in the placebo arm. The median number of tablets taken each month was 9.5, with a median of five sexual intercourse encounters.

The results, …

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