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The antibiotic course has had its day

BMJ 2017; 358 doi: (Published 26 July 2017) Cite this as: BMJ 2017;358:j3418

Rapid Response:

Re: The antibiotic course has had its day

Before reading the article I suspected it could be non-sense. After reading it I am pleased with an excellent thoughtful article. There is no new information in this work, no new experiments, test, essays; what is different in this article is the rational construction it makes of (widely?) known facts. The authors change the epistemic frame (1-2). They stop thinking in terms of the illness and the particular bacteria producing it in the particular individual and rather think in terms of the antibiotic altering the ecosystem of the individual (including, but not only, the intestinal flora) and the well being of the human species. Changing the epistemic frame makes possible new questions and new research directions, and this is precisely what the article does. An excellent article, no doubt about it!

(1) ,J Piaget and R García. Psychogenesis and the History of Science, Columbia University Press (New York)}, 1989,
(2) H G Solari, Epistemic considerations on research about Flavivirus induced fevers. Journal of Fever 1 (1), March 2017.

Competing interests: No competing interests

03 August 2017
Hernán G Solari
Universidad de Buenos Aires
Department of Physics, Facultad de Ciencias Exactas y Naturales, UBA. 1648 Buenos Aires, Argentina