US government website for collecting adverse events after vaccination is inaccessible to most users

BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j2449 (Published 19 May 2017) Cite this as: BMJ 2017;357:j2449

Re: US government website for collecting adverse events after vaccination is inaccessible to most users

Peter Doshi [1] may be interested in the results of the long delayed vaccinateted vs. unvaccinated study by Mawson et al [2]:

"A convenience sample of 666 children was obtained, of which 261 (39%) were unvaccinated. The vaccinated were less likely than the unvaccinated to have been diagnosed with chickenpox and pertussis, but more likely to have been diagnosed with pneumonia, otitis media, allergies and NDD. After adjustment, vaccination, male gender, and preterm birth remained significantly associated with NDD. However, in a final adjusted model with interaction, vaccination but not preterm birth remained associated with NDD, while the interaction of preterm birth and vaccination was associated with a 6.6-fold increased odds of NDD (95% CI: 2.8, 15.5). In conclusion, vaccinated homeschool children were found to have a higher rate of allergies and NDD than unvaccinated homeschool children. While vaccination remained significantly associated with NDD after controlling for other factors, preterm birth coupled with vaccination was associated with an apparent synergistic increase in the odds of NDD. Further research involving larger, independent samples and stronger research designs is needed to verify and understand these unexpected findings in order to optimize the impact of vaccines on children’s health."

Meanwhile, British news reports in recent months suggest that autism rates in young children are spinning ever further out of control [3,4,5]. It is noteworthy that the problem seems to be supply led rather than diagnosis led. The reports focus on the failure institutional capacity, not why it is happening or how it could possibly be sustainable. If you map the figure in the BBC report from five SW London boroughs on to the entire capital, that is of the order of 10,000 new cases a year.

Is it not time we got our heads out of the sand?

[1] Peter Doshi, 'US government website for collecting adverse events after vaccination is inaccessible to most users' BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j2449
[2] Anthony R Mawson, Brian D Ray, Azad R Bhuiyan, Binu Jacob 'Pilot comparative study on the health of vaccinated and unvaccinated 6- to 12- year old U.S. children', Journal of Translational Science, 24 April 2017, http://www.oatext.com/Pilot-comparative-study-on-the-health-of-vaccinate...
[3] Helen McArdle, 'Call for investigation as 20 young Scots a day are rejected fro mental health care', Sunday Herald 20 December 2016, http://www.heraldscotland.com/news/14975962.Call_for_investigation_as_20...
[4] Brett Campbell, 'Autism assessment list now at crisis level, says MLA', 22 December 2016 http://www.belfasttelegraph.co.uk/news/northern-ireland/autism-assessmen...
[5] Jane Dreaper, 'Autism diagnoses 'could be reduced under NHS plan'', BBC News 27 May 2017, http://www.bbc.co.uk/news/health-40058482

Competing interests: No competing interests

29 May 2017
John Stone
UK Editor
London N22