Tailoring your blood pressure target . . . and other storiesBMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j2193 (Published 11 May 2017) Cite this as: BMJ 2017;357:j2193
Individual targets for blood pressure
The “one target fits all” model for lowering high blood pressure makes little sense, but it is proving difficult to replace. In 2015 the SPRINT trial (N Engl J Med doi:10.1056/NEJMoa1511939) showed that having a lower target blood pressure in high risk patients reduced the number of cardiovascular events, though with a high number needed to treat and more serious adverse events. A team led by John Spertus in Texas has analysed the published data and developed prediction models to tailor the intensity of blood pressure control based on the projected risk and benefit for each patient (Circ Cardiovasc Qual Outcomes doi:10.1161/CIRCOUTCOMES.117.003624). This model, and others like it, will now need to be tested in long term studies.
Long term opioid use after surgical analgesia
Chronic opioid use, and with it opioid …