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Letters NICE on sepsis

Sepsis quality standards are laudable but have low specificity

BMJ 2017; 357 doi: (Published 25 April 2017) Cite this as: BMJ 2017;357:j1974
  1. Ed Moran, consultant in infectious disease,
  2. Melinda Munang, registrar in infectious disease,
  3. Cathleen Chan, core medical trainee,
  4. Saleem Chaudhri, core medical trainee,
  5. Methini Himayakanthan, core medical trainee,
  6. Steven Laird, registrar in infectious disease,
  7. Amy Moltu, foundation year doctor,
  8. Natasha Naworynsky, foundation year doctor,
  9. Christopher Pollard, registrar in infectious disease,
  10. Tahir Saeed, foundation year doctor,
  11. Paul Scott, clinical scientist,
  12. Maya Sussman, core medical trainee,
  13. Shaun Thein, core medical trainee,
  14. George Trafford, registrar in infectious disease,
  15. Ariyur Balaji, consultant in acute medicine and infectious disease,
  16. Neil Jenkins, consultant in infectious disease
  1. Departments of Infection and Acute Medicine, Heart of England NHS Foundation Trust, Birmingham, UK
  1. ed.moran{at}

The proposed quality standards for sepsis from the National Institute for Health and Care Excellence (NICE) are laudable in principle.1 But the practical reality of applying them to the 2016 NICE sepsis definition2 is unclear.

To establish the proportion of patients classified as septic by NICE guidance compared with previous criteria based on systemic inflammatory response syndrome (SIRS), we retrospectively reviewed the initial …

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