Intended for healthcare professionals

CCBYNC Open access

Rapid response to:

Research

Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data

BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j1909 (Published 09 May 2017) Cite this as: BMJ 2017;357:j1909

Rapid Response:

Re: Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data

I give an explanation of the fact that NSAIDS increase the risk of MI here:

Heitor Reis, A. “On the etiology of cardiovascular diseases: A new framework for understanding literature results”, Medical Hypotheses, 92, 94–99 (2016)
Heitor Reis, A. “Acidemia and blood free fatty acids: analysis of cardiovascular risk factors in a new context.” Discovery Medicine 23(126):183-188 (2017) (OPEN ACCESS)

Essentially, NSAIDs cause acidemia, which in the context of high concentrations of Free Fatty Acids increases the risk of MI

Competing interests: No competing interests

04 June 2017
Antonio H Reis
Full Professor
University of Evora
R. Romão Ramalho, 59, 7002-554 Évora, Portugal.