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All patients with colorectal cancer should be tested for genetic condition, NICE advises

BMJ 2017; 356 doi: https://doi.org/10.1136/bmj.j998 (Published 24 February 2017) Cite this as: BMJ 2017;356:j998
  1. Anne Gulland
  1. London

Everyone who has colorectal cancer diagnosed should be tested for an inherited genetic condition called Lynch syndrome, new guidance states.1

The National Institute for Health and Care Excellence (NICE) recommends microsatellite instability testing or immunohistochemistry to detect abnormalities that may indicate the syndrome.

Lynch syndrome, the most common cause of hereditary bowel cancer, has also been linked to an increased risk of developing other cancers including womb, ovarian, and stomach. People with the condition who develop colorectal …

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