Uncontrolled Confounding Playing Here Again???
Although this study is large and the results looks interesting and intriguing and stratified, not all potential confounders were dealt with--for example, ethnicity.
So, we have to agree with Prof. Sattar that this is not randomised clinical trial evidence (1) but rather only observational evidence.
1. Journal of the American College of Cardiology Volume 66, Issue 11, September 2015. DOI: 10.1016/j.jacc.2015.07.021
Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitor-Based Treatment on Cardiovascular Outcomes in Hypertensive Blacks Versus Whites
Gbenga Ogedegbe, Nirav R. Shah, Christopher Phillips, Keith Goldfeld, Jason Roy, Yu Guo, Joyce Gyamfi, Christopher Torgersen, Louis Capponi, Sripal Bangalore
Competing interests: No competing interests