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A giant fungating tumour on the buttock

BMJ 2017; 356 doi: https://doi.org/10.1136/bmj.i6440 (Published 02 February 2017) Cite this as: BMJ 2017;356:i6440

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A giant fungating tumour on the buttock ? Verrucous carcinoma

Dear Editor,

This is a very interesting case report. An important clinicopathological differential diagnosis in this case is a verrucous carcinoma (very well differentiated squamous cell carcinoma). Histologically, this can look extremely benign and can mimic a seborrhoeic keratosis / benign squamous keratosis. I have seen a number of cases like this, where the initial pathology diagnosis is benign, but after review of the slides and discussion at a multidisciplinary meeting the final diagnosis is a verrucous carcinoma. This differential diagnosis should be considered in this case.

Competing interests: No competing interests

05 February 2017
Joseph P Houghton
Clinical Senior Lecturer / Consultant Histopathologist
Queen's University Belfast
Centre for Medical Education, Queen's University Belfast