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Statins are linked to reduced Alzheimer’s risk, study finds

BMJ 2016; 355 doi: https://doi.org/10.1136/bmj.i6675 (Published 13 December 2016) Cite this as: BMJ 2016;355:i6675
  1. Susan Mayor
  1. London

Regular use of statins is associated with reduced risk of Alzheimer’s disease, but this reduction varies in people of different ethnicity and among different statins, a retrospective analysis of US clinical data has shown.1

Serum cholesterol levels are associated with the deposition of beta amyloid and the pathology of Alzheimer’s disease, so lowering cholesterol may influence its onset and progression. Research has found that statins may protect against the risk of Alzheimer’s, but randomised trials have been inconclusive, and previous cohort studies cannot be widely generalised.

Researchers in the new study analysed administrative claims data from a 20% …

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