SSRIs double the risk of suicide and violence in healthy adults

Selective serotonin and serotonin-norepinephrine (noradrenaline) reuptake inhibitors double the risk of suicide and violence in healthy adults with no signs of a mental disorder, a systematic review has found.

The review, published in the Journal of the Royal Society of Medicine, is the first to analyse trials of these antidepressants in healthy adults.1 Researchers from the Nordic Cochrane Centre and University of Copenhagen in Denmark identified 130 double blind, randomised placebo controlled trials through PubMed and Embase and 29 …