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Orthostatic hypotension linked to risk of dementia, finds study

BMJ 2016; 355 doi: (Published 12 October 2016) Cite this as: BMJ 2016;355:i5490
  1. Susan Mayor
  1. London

Orthostatic hypotension is associated with a 15% rise in long term risk of dementia, including Alzheimer’s disease, a follow-up study has found.

Orthostatic hypotension affects 20-30% of elderly people and is a common cause of transient cerebral hypoperfusion. The study investigated the future risk of dementia in people with orthostatic hypotension, defined as ≥20 mm Hg drop in systolic blood pressure or ≥10 mm Hg drop in diastolic blood pressure within three minutes of standing up after lying down for five …

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