Intended for healthcare professionals


Five minutes with . . . John Ioannidis

BMJ 2016; 354 doi: (Published 28 September 2016) Cite this as: BMJ 2016;354:i5184
  1. Susan Mayor
  1. London

The Stanford University professor talks about the problems with meta-analyses

“We have an epidemic of deeply flawed meta-analyses, with the number published each year having increased by more than 2600% over the past 20 years, compared with only 50% for research studies of all types listed on PubMed.1

“There is now massive production of unnecessary, misleading, and conflicted systematic reviews and meta-analyses. While these designs represent the highest level of evidence, they are often massively misused, and …

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