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Most patients taking warfarin do not maintain stable INR values

BMJ 2016; 354 doi: (Published 10 August 2016) Cite this as: BMJ 2016;354:i4402
  1. Jacqui Wise
  1. London

Most patients taking warfarin who have stable international normalised ratio (INR) values do not maintain them over time, a study published in JAMA has found. The finding challenges the belief that patients with good outcomes from warfarin should keep taking it rather than switching to non-vitamin K oral anticoagulants.1

Warfarin substantially decreases stroke risk in patients with atrial fibrillation, but it has a narrow therapeutic window (INR …

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