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Moderate LDL cholesterol reduction with statins shows similar benefit to aggressive lipid lowering in ischaemic heart disease

BMJ 2016; 353 doi: (Published 22 June 2016) Cite this as: BMJ 2016;353:i3437
  1. Susan Mayor
  1. London

Moderate reduction of low density lipoprotein (LDL) cholesterol with statins achieved similar reductions in adverse cardiac outcomes in patients with ischaemic heart disease to aggressive lipid lowering, shows a retrospective cohort study.1

The study, reported in JAMA Internal Medicine, compared the risk for major cardiac events in patients with ischaemic heart disease treated with statins and achieving a low LDL cholesterol level of ≤70 mg/dL with patients achieving moderate levels (70.1 to 100 mg/dL) or high levels (100.1 to 130 mg/dL) …

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