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Weight loss drugs are compared for effectiveness

BMJ 2016; 353 doi: (Published 15 June 2016) Cite this as: BMJ 2016;353:i3330
  1. Jacqui Wise
  1. London

The obesity drug phentermine-topiramate was associated with the highest odds of achieving weight loss of at least 5% when compared with four other agents, a meta-analysis and systematic review published in JAMA has found.1

The review found that five weight loss drugs, when compared with placebo, were each associated with achieving at least 5% weight loss after a year in overweight or obese adults. The five drugs—orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide—have all been approved by …

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