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Whole grains and public health (Original Research)
In the above review the intake of whole grain foods is associated with (to quote) “a beneficial effect on glucose insulin homeostasis, blood lipids and gastrointestinal health”. Under the last heading could be included also their effect on the prevalence of peptic ulceration. Geographically the prevalence of duodenal ulceration is less in regions where the staple diet is composed of whole grain foods such as unrefined wheat or maize, certain millets and pulses, and soya bean, and more in regions where the staple diet is of refined or starchy foods such as refined wheat or maize, white rice, cassava, yams, sweet potato or green bananas[1]. Experiments on different rat peptic ulcer models showed that these whole grain foods contain protective factors not only against duodenal ulceration but also against gastric ulceration and lesions due to aspirin. This protective activity was shown to lie in the lipid fraction present in the whole grain foods, particularly in the bran and the germ[2], and that this activity lay in the phospholipid and phytosterol content of the lipid[3].
References:-
1 Tovey F I. Staple diets and duodenal ulcer prevalence. International Health 2009; 1: 124-132.
2 Jayaraj A P, Tovey F I, Hobsley M. Duodenal ulcer prevalence: Research into the nature of possible protective dietary lipids. Phytother Res 2003; 17: 391-398.
3 Tovey F I. Role of dietary phospholipids and phytosterols in protection against peptic ulceration as shown by experiments on rats. World J Gastroenterol 2015; 21(5): 1377-1384.
Competing interests:
No competing interests
19 June 2016
Frank I Tovey
Retd. Consultant Surgeon
North Hampshire Hospital, Ex. Senior Research Fellow, Dept. of Surgery, University College, London.London
Re: Whole grains and public health
Whole grains and public health (Original Research)
In the above review the intake of whole grain foods is associated with (to quote) “a beneficial effect on glucose insulin homeostasis, blood lipids and gastrointestinal health”. Under the last heading could be included also their effect on the prevalence of peptic ulceration. Geographically the prevalence of duodenal ulceration is less in regions where the staple diet is composed of whole grain foods such as unrefined wheat or maize, certain millets and pulses, and soya bean, and more in regions where the staple diet is of refined or starchy foods such as refined wheat or maize, white rice, cassava, yams, sweet potato or green bananas[1]. Experiments on different rat peptic ulcer models showed that these whole grain foods contain protective factors not only against duodenal ulceration but also against gastric ulceration and lesions due to aspirin. This protective activity was shown to lie in the lipid fraction present in the whole grain foods, particularly in the bran and the germ[2], and that this activity lay in the phospholipid and phytosterol content of the lipid[3].
References:-
1 Tovey F I. Staple diets and duodenal ulcer prevalence. International Health 2009; 1: 124-132.
2 Jayaraj A P, Tovey F I, Hobsley M. Duodenal ulcer prevalence: Research into the nature of possible protective dietary lipids. Phytother Res 2003; 17: 391-398.
3 Tovey F I. Role of dietary phospholipids and phytosterols in protection against peptic ulceration as shown by experiments on rats. World J Gastroenterol 2015; 21(5): 1377-1384.
Competing interests: No competing interests