Letters
Clinical risk factors for pre-eclampsia determined in early pregnancy
Authors’ reply to Thilagnathan
BMJ 2016; 353 doi: https://doi.org/10.1136/bmj.i2889 (Published 24 May 2016) Cite this as: BMJ 2016;353:i2889
- Joel G Ray, clinician-scientist1,
- Emily Bartsch, medical student2
- 1Departments of Medicine, Health Policy Management and Evaluation, and Obstetrics and Gynecology, St Michael’s Hospital, University of Toronto, Toronto, Canada
- 2University of Toronto, Toronto, Canada
- rayj{at}smh.ca
In response to Thilagnathan’s comments,1 our paper identified several single risk factors that confer enough risk to justify aspirin prophylaxis in pregnancy (http://bit.ly/27Gw8LQ).2 For other risk factors, we recommend that two or more need to be present, again, based on our recent study. Maternal age over 40 years requires the presence of a second risk factor because its number needed to prevent was greater than 250.
We agree that our systematic review could …
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