Intended for healthcare professionals

Rapid response to:

Clinical Review State of the Art Review

Sepsis: pathophysiology and clinical management

BMJ 2016; 353 doi: (Published 23 May 2016) Cite this as: BMJ 2016;353:i1585

Chinese translation


Rapid Response:

Penicillin is still the best for streptococcus pyogenes and pneumococcal pneumonia!

Dear Sir,

I would like to congratulate Dr. Walid Al-Wali.

And most important is the message of Prof. Cleary and Prof. Rohde:
Streptococci are intracellular microbes.

You will not find them by swab.

And the the blood-stream infection by streptococci is only the tip of the iceberg of not diagnoses streptococcal infections.

And the best treatment is penicillin.

Best wishes

Yours Friedrich Flachsbart

J. J. Ferretti, D. L. Stevens, V. A. Fischetti: Streptococcus pyogenes: Basic Biology to clinical manifestations. (Internet)
University of Oklahoma Health Sciences, 2016.

M. Rohde, P. P. Cleary: Adhesion and invasion of Streptococcus pyogenes into host cells and clinical relevance of intracellular streptococci.
a. a. O.

Competing interests: No competing interests

02 July 2016
Friedrich Flachsbart
retired gp
Germany, 37085 Göttingen, Eisenacher Str. 6