Proton pump inhibitors may be linked to dementia risk

Proton pump inhibitor use may be associated with an increased risk of dementia, a German prospective cohort study published in JAMA Neurology shows.1 These are widely used for treating gastrointestinal disease, and their use has increased among older patients.

The researchers used observational data covering 2004-11 obtained from the largest German statutory health insurer, Allgemeine Ortskrankenkasse. The insurer covers …