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Proton pump inhibitors are associated with risk of chronic kidney disease, study finds

BMJ 2016; 352 doi: (Published 12 January 2016) Cite this as: BMJ 2016;352:i128
  1. Jacqui Wise
  1. 1London

Proton pump inhibitor use is associated with a 20-50% higher risk of incident chronic kidney disease, an observational US study published in JAMA Internal Medicine has found. However, the authors said that further research was needed to determine whether the link is causal.1

Researchers followed up 10 482 participants in the Atherosclerosis Risk in Communities study for a median of 13.9 years and found that the risk of chronic kidney disease was 50% higher in self reported proton pump inhibitor users than in non-users.

They found 56 incident chronic kidney events among …

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