Re: Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial
Ethical approval for this trial was obtained by the Independent Ethics Committees of the Hannover Medical School (No. 5986 M). I would be interested in any comments on whether this design generated some kind of debate inside the Committee. A previous reply stated that it is rational to compare analgesic anti-inflammatory drugs with antibiotics in uncomplicated urinary tract infection in women. The argument is that relief of symptoms and cure of infection are different aspects. The problem is that the two aspects are put on the same level; but is it ethical? A mere palliative attitude for infection is assumed when potentially curative means are too aggressive, of dubious effectiveness and the prognosis of the patient is too poor. What would have done if I had participated in this Ethics Committee discussing the approval for a trial that supports treating infections with antibiotics? I do not know...
Competing interests: No competing interests