Letters Diagnosing miscarriage

Authors’ reply to Fountain and colleagues

BMJ 2015; 351 doi: https://doi.org/10.1136/bmj.h5852 (Published 04 November 2015) Cite this as: BMJ 2015;351:h5852
  1. Tom Bourne, professor and consultant gynaecologist1,
  2. Jessica Preisler, clinical research fellow1,
  3. Ben Van Calster, professor2,
  4. Dirk Timmerman, professor2
  1. 1Queen Charlotte’s and Chelsea Hospital, Imperial College, London W12 0HS, UK
  2. 2Department of Development and Regeneration, KU Leuven, Belgium
  1. tbourne{at}imperial.ac.uk

We appreciate Fountain and colleagues’ comments.1 2 We did consider how the dates of the last menstrual period might affect a possible diagnosis of miscarriage, and we draw readers’ attention to the sub-section of the results that deals with this—the revised criteria for diagnosing miscarriage contained in table 5 and fig 2.

We did not consider menstrual cycle length as a variable. We thought that making assumptions about the timing of ovulation in these circumstances, coupled with the known variations in the ovulation-implantation interval,3 would make this difficult to integrate into reliable guidelines that would be …

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