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Insulin has potential to prevent type 1 diabetes in high risk children, say researchers

BMJ 2015; 350 doi: (Published 22 April 2015) Cite this as: BMJ 2015;350:h2116
  1. Jacqui Wise
  1. 1London

High dose insulin given to children at risk of developing type 1 diabetes resulted in an immune response without hypoglycaemia, a double blind, placebo controlled pilot study has found.

The German researchers said that the findings, published in JAMA,1 support the need for a phase III trial to determine whether oral insulin can prevent islet autoimmunity and diabetes in children genetically at risk.

The incidence of type 1 diabetes has increased in the past few …

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