Intended for healthcare professionals

Rapid response to:

Analysis Too Much Medicine

Overdiagnosis of bone fragility in the quest to prevent hip fracture

BMJ 2015; 350 doi: (Published 26 May 2015) Cite this as: BMJ 2015;350:h2088

Rapid Response:

Re: Overdiagnosis of bone fragility in the quest to prevent hip fracture

The International Society for Clinical Densitometry (ISCD) is a multidisciplinary, nonprofit organization whose mission is to advance excellence in the assessment of skeletal health. The ISCD wishes to support the comments from the National Bone Health Alliance (NBHA), International Osteoporosis Foundation (IOF), American Society for Bone Mineral Research (ASBMR) and others who have objected to the tone and content of the article. In their provocative article, Teppo Järvinen and colleagues have distorted and misrepresented the osteoporosis burden. The following simple statements of fact are supported by high-level scientific evidence and commonsense:

• Osteoporosis is a disease with major health consequences that include death,
• Osteoporosis remains severely underdiagnosed and undertreated,
• DXA and FRAX are able to identify those at high fracture risk,
• Approved treatments for osteoporosis are effective, safe and additive to non-pharmacological interventions (diet, exercise and fall prevention).

William D. Leslie, MD, MSc, FRCPC, CCD
ISCD President

Competing interests: Speaker fees and/or research grants (all paid to facility): Amgen, Eli Lilly, Novartis, Genzyme.

22 July 2015
William D Leslie
Professor of Medicine and Radiology
University of Manitoba
C5121-409 Tache Avenue, Winnipeg, Canad R2H 2A6