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Genetic changes likely to predict response to immunotherapy in bowel cancer are identified

BMJ 2015; 350 doi: (Published 24 March 2015) Cite this as: BMJ 2015;350:h1590
  1. Susan Mayor
  1. 1London

Genetic changes associated with how the immune system responds to bowel cancer have been identified by researchers, from the results of a study published in Oncoimmunology that could help to identify patients likely to respond to different targeted immunotherapy treatments.1

The density of tumour infiltrating lymphocytes is prognostic and predictive in colorectal cancer, but the genetic factors driving this immune response have previously been unclear. Researchers analysed data on 195 patients with colorectal cancer in the Cancer …

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