Intended for healthcare professionals


PCORI’s ambitious efforts to promote transparency and dissemination of research findings

BMJ 2014; 349 doi: (Published 20 October 2014) Cite this as: BMJ 2014;349:g6261
  1. José G Merino, US clinical research editor,
  2. Elizabeth Loder, acting head of research
  1. 1The BMJ, USA
  1. Correspondence to: J G Merino jmerino{at}

Lots to applaud, but still a few ends to tie up

The Patient Centered Outcomes Research Institute (PCORI), an independent, non-profit organization, was set up to fund patient centered comparative clinical effectiveness research under the US Patient Protection and Affordable Care Act of 2010. From its inception, PCORI has worked to make the research it funds transparent, relevant, and accessible to end users, including patients. Patients and caregivers work with clinicians, researchers, and other stakeholders to establish funding priorities and evaluate grant proposals.1 To receive funding, researchers must show that patients participated in the design and conduct of the study.

Now, as required by the legislation that established it, PCORI has proposed a peer review process to critically appraise the scientific rigor and adherence to the institute’s methodological standards of completed research and to make the results available to the public. The suggested process requires studies to be registered on a site that is appropriate for their design (such as for clinical trials and observational studies). Three months after completion of the data analysis specified in the study protocol, researchers will be required to submit a draft report of the findings to PCORI, and this will be peer …

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