The difficulty in evaluating all findings in study on use of macrolides in mother and child and risk of infantile hypertrophic pyloric stenosis

Lund and colleagues report a 30-fold risk of infantile hypertrophic pyloric stenosis with the use of macrolide antibiotics during the first 0-13 days of a child’s life.1 This is either a very strong association or too good to be true.

The authors used the Danish national databases, which linked the dispensing of drugs from community …