To the editor,
Although Dr Bao Wei et al. answered some of my questions (1), I still have concerns.
First, although the authors explained the reasons why three studies (2-4) we mentioned were excluded, it is still unclear why many studies on the relationship between fruit or vegetable intake and specific cancer mortality were finally excluded.
Second, as there was publication bias for their results, I still question whether the trim and fill method used by the authors can address the publication bias simply from a statistical perspective.
1. Authors' reply on the systematic review and does-response meta-analysis of fruit and vegetable consumption in relation to mortality.http://www.bmj.com/content/349/bmj.g4490/rr/762968
2. Mann JI, Appleby PN, Key TJ, Thorogood M. Dietary determinants of ischaemic heart disease in health conscious individuals. Heart. 1997;78:450-5.
3. Ness AR, Maynard M, Frankel S, Smith GD, Frobisher C, Leary SD, Emmett PM, Gunnell D. Diet in childhood and adult cardiovascular and all cause mortality: The boyd orr cohort. Heart. 2005;91:894-8.
4. Lo YT, Chang YH, Wahlqvist ML, Huang HB, Lee MS. Spending on vegetable and fruit consumption could reduce all-cause mortality among older adults. Nutr J. 2012;11:113.
Competing interests: No competing interests