Intended for healthcare professionals

Letters Adverse effects of statins

Muscular adverse effects are common with statins

BMJ 2014; 348 doi: (Published 11 June 2014) Cite this as: BMJ 2014;348:g3724
  1. Peter C Gøtzsche, professor1
  1. 1Nordic Cochrane Centre, Copenhagen, Denmark
  1. pcg{at}

The 2011 Cochrane review of statins for the primary prevention of cardiovascular disease reported a risk ratio of 1.03 for muscle pain—3% more patients developed muscle pain on the drug than on placebo.1 However, industry funded randomised trials are notoriously unreliable …

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