Intended for healthcare professionals


Adverse effects of statins

BMJ 2014; 348 doi: (Published 15 May 2014) Cite this as: BMJ 2014;348:g3306

Re: Adverse effects of statins

Independent of the proper percentage referred to, we agree with F. Godlee's article because one of us said in 1991 that statins are dangerous if administered in hyperdislipidemics affected by unrecognized Co Q10 Deficiency Syndrome (1,2). Ten years later, the mass-media all over the world announced rhabdomyolysis and death caused by cerivastatin if prescribed in association with other anticholesterolemic drugs (fibrates). Unfortunately, the above-referred data of the research of one of us have been unfortunately over-looked.

As a matter of fact, in the above-mentioned article it is described, for the first time, the method to bedside recognize “clinically”, by means of a new, original physical semeiotics, the Quantum Biophysical Semeiotics, Co Q10 Deficiency syndrome, even initial and asymptomatic.

Co Q10 is an essential coenzyme, scavenger of free radicals, and unavoidable in reaching the normal free energy level in every cell of the body, necessary for the life of all biological systems, including heart and skeletal muscle. Finally, statins have to be administered exclusively to patients affected by CAD and CVD with an Inherited Real Risk (3,4).


1) Stagnaro-Neri M., Stagnaro S., Carenza di Co Q10 secondaria a terapia ipolipidemizzante diagnosticata con la Percussione Ascoltata. Epat.(S.E.U.) 37, 17, 1990, and Settimana Italiana di Dietologia, 9-13 Aprile 1991, Merano. Atti, pg. 65.
2) Stagnaro-Neri M, Stagnaro S. C0Q10 in the prevention and treatment of primary osteoporosis. Preliminary data. Clin Ter. 1995 Mar;146(3):215-9 (MEDLINE)
3) Sergio Stagnaro and Simone Caramel. The Inherited Real Risk of Coronary Artery Disease, Nature PG., EJCN, European Journal Clinical Nutrition, Nature PG., [Medline]
4)Stagnaro Sergio. CAD Inherited Real Risk, Based on Newborn-Pathological, Type I, Subtype B, Aspecific, Coronary Endoarteriolar Blocking Devices. Diagnostic Role of Myocardial Oxygenation and Biophysical-Semeiotic Preconditioning. International Atherosclerosis Society., 29 April, 2009

Competing interests: No competing interests

17 May 2014
Sergio Stagnaro
Director of Quantum Biophysical Semeiotics Research Laboratory
Caramel Simone, Marchionni Marco
Quantum Biophysical Semeiotics Research Laboratory
Via E. Piaggio 23/8 16039 Riva Trigoso (Genoa) Italy