Letters News story on Tamiflu study

Principal author of PRIDE study responds to news story in The BMJ claiming that the study was based on “flawed” analysis

BMJ 2014; 348 doi: https://doi.org/10.1136/bmj.g2935 (Published 29 April 2014) Cite this as: BMJ 2014;348:g2935
  1. Jonathan S Nguyen-Van-Tam, clinical professor of health protection, and senior author, PRIDE Consortium1
  1. 1University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
  1. jonathan.van-tam{at}nottingham.ac.uk

On 19 March 2014, researchers from the PRIDE (Post-pandemic Review of anti-Influenza Drug Effectiveness) Consortium published the first outputs from a project investigating the effectiveness of neuraminidase inhibitors against outcomes of public health importance during the 2009 flu pandemic in the Lancet Respiratory Medicine.1 2 The headline results suggested that neuraminidase inhibitors were associated with statistically significant reductions in mortality: overall adjusted odds ratio 0.81 (95% CI 0.70 to 0.93; P=0.0024) versus no treatment and 0.50 …

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