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Letters Vitamin D and multiple outcomes

Authors’ reply to Boucher

BMJ 2014; 348 doi: (Published 29 April 2014) Cite this as: BMJ 2014;348:g2927
  1. Evropi Theodoratou, research fellow1,
  2. John P A Ioannidis, professor2
  1. 1Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
  2. 2Stanford Prevention Research Center, Departments of Medicine and Health Research and Policy, Stanford University School of Medicine, and Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, CA, USA
  1. e.theodoratou{at}

Boucher presents several arguments for substantial benefits from vitamin D supplementation,1 but this is not clearly shown in our review.2

Given that we selected only one review per outcome for our analysis, the risk of overlap of original studies is minimal for any given outcome. Boucher’s comments on the importance of supplement doses …

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