Intended for healthcare professionals

Letters Vitamin D and risk of cause specific death

Vitamin D supplements do not reduce mortality risk

BMJ 2014; 348 doi: (Published 29 April 2014) Cite this as: BMJ 2014;348:g2860
  1. Mark J Bolland, associate professor of medicine1,
  2. Andrew Grey, associate professor of medicine1,
  3. Ian R Reid, professor of medicine1
  1. 1Department of Medicine, University of Auckland, Private Bag 92019, Auckland, New Zealand
  1. m.bolland{at}

In their meta-analysis of 22 randomised controlled trials (RCTs), Chowdhury and colleagues report that, overall, vitamin D supplements had no effect on mortality, but a subgroup analysis suggested mortality was reduced in 14 trials of vitamin D3 and not in eight trials of vitamin D2.1 However, three of the trials classified as vitamin D3 trials actually studied calcitriol …

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