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Letters Are we overusing IVF?

Increase in older women presenting as unexplained subfertility may explain overuse of in vitro fertilisation

BMJ 2014; 348 doi: (Published 19 February 2014) Cite this as: BMJ 2014;348:g1583
  1. Sesh Kamal Sunkara, subspecialist in reproductive medicine1,
  2. Srividya Seshadri, subspecialist in reproductive medicine2
  1. 1Queen Elizabeth Hospital, King’s Healthcare Partners (Guy’s and St Thomas NHS Foundation Trust), London, UK
  2. 2Guy’s Hospital, London, UK
  1. sksunkara{at}

Kamphuis and colleagues analysed the overuse of in vitro fertilisation (IVF) treatment, focusing on the newer indications.1 The incidence of unexplained subfertility as an indication for IVF has undoubtedly increased, but why? With cited incidences being based on registries from Western countries, the most likely reason is the increase in female childbearing age and ovarian senescence in older women …

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