Re: Should people at low risk of cardiovascular disease take a statin?
In a developing country like India every prescription for cardiovascular disease (TIA, Stroke, Coronary syndrome, hypertension) ends with the prescription of a statin. The day is not far away that it will be available over the counter like aspirin. The age old product nicotinic acid is totally forgotten by medical fraternity.
How a combination of statin + Vitamin-D3 is effective remains a dilemma. In cardiovascular diseases prevention is better than cure. Careful following patient taking statin for side effect: myalgia, easy fatigue, rhabdomyolysis, hematuria, renal failure. Early most sign of statin toxicity is proximal muscle weakness easily detected in routine clinical examination.
The anti-inflammatory action of statins may arrest the progression of dementia. Inhibition of liberated metalloproteinase stabilizes the life threatening coronary plaque in coronary syndrome.
Overall benefits override the risk and side effects of statin. In medical fraternity statin and aspirin are twin sisters in 21st century and go hand in hand.
Competing interests: No competing interests