Research News

Candidate malaria vaccine becomes less effective over time, study shows

BMJ 2013; 347 doi: (Published 09 October 2013) Cite this as: BMJ 2013;347:f6098
  1. Jacqui Wise
  1. 1London

A candidate vaccine against malaria has been shown to almost halve the number of malaria cases in young children but only to reduce cases by a quarter in infants. The effectiveness of the vaccine was also found to decline over time, the 18 month results from a large phase III trial show.

However, the vaccine’s manufacturer, GlaxoSmithKline, said that it was encouraged by the results and plans to submit a regulatory application to the European Medicines Agency in 2014. If it succeeds this will be the world’s first malaria vaccine.

The results were presented at the Multilateral Initiative on Malaria Pan-African conference in …

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