Letters Polypill

Faulty logic justifies aspirin use for primary prevention of cardiovascular disease

BMJ 2013; 347 doi: https://doi.org/10.1136/bmj.f5021 (Published 09 August 2013) Cite this as: BMJ 2013;347:f5021
  1. Simon J Thornley, research fellow1,
  2. Federica Barzi, senior research fellow, renal and metabolic division2
  1. 1Section of Epidemiology and Biostatistics, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
  2. 2George Institute for Global Health, Camperdown, NSW, Australia
  1. s.thornley{at}auckland.ac.nz

We are sceptical about the use of the polypill as a “panacea.” In studies that justify the use of the individual constituents of the pill, optimism about the drugs’ beneficial effects sometimes contradicted the statistical evidence presented.1

For example, a paper published 12 years ago in Heart is cited widely to support the use of aspirin for the prevention …

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