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Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years

BMJ 2013; 347 doi: https://doi.org/10.1136/bmj.f4539 (Published 13 August 2013) Cite this as: BMJ 2013;347:f4539

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Re: Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years

Dear Editor,

Thank you very much for publishing this paper by: Reynolds RM, Allan KM, Raja EA, Bhattacharya S, McNeill G, Hannaford PC, et al. Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years. BMJ (Clinical research ed.) 2013;347 f4539.

The paper found that maternal obesity not only increases the chance of cardiovascular disease in adult offspring, but also all-cause mortality which is concerning due to the increase in maternal obesity throughout the world.

Although the association has been found a lot of other things have an impact on cardiovascular events through a person’s lifetime. In the scenario that a mother has a high BMI than it is most likely due to her lifestyle, which may consist of a lack of exercise and unhealthy diet [1]. Children usually behave in a similar manner to their parents so therefore if the parents lead a sedentary lifestyle than this of course will cause the children to follow suit. Therefore obesity will become a family trait leading to an increased risk of obesity for the whole family.

Also, the study size is large in terms of participants; however, it is very limited in terms of location. The problem of maternal obesity has been identified as worldwide by the authors so a multicentred approach would have given more reliable results as the association, if proven, would have been proven across many different ethnicities. A similar study could have been done in South Asia [2] to prove that the association is true throughout all ethnicities.

Thank you

References

(1)Roberts CK, Izadpanah A, Angadi SS, Barnard RJ. Effects of an Intensive Short-term Diet and Exercise Intervention: Comparison between Normal Weight and Obese Children. American journal of physiology. Regulatory, integrative and comparative physiology 2013.

(2)Bryant M, Santorelli G, Lawlor DA, Farrar D, Tuffnell D, Bhopal R, et al. A comparison of South Asian specific and established BMI thresholds for determining obesity prevalence in pregnancy and predicting pregnancy complications: findings from the Born in Bradford cohort. International journal of obesity (2005) 2013.

Competing interests: No competing interests

20 August 2013
Aman Jain
Medical Student
Dr Ari Manuel, SPR Respiratory Medicine, Oxford University Hospitals, Mobile 07958938321, Fax 01865741841, ari.manuel@ouh.nhs.uk
Imperial College London
Imperial College London, South Kensington Campus, Exhibition Rd, London SW7 2AZ