Intended for healthcare professionals

Letters Recurrent UTI in non-pregnant women

Is “nitrofurantoin lung”on the increase?

BMJ 2013; 346 doi: (Published 18 June 2013) Cite this as: BMJ 2013;346:f3897
  1. Adam D L Marshall, respiratory registrar1,
  2. Owen J Dempsey, consultant chest physician1
  1. 1Chest Clinic C, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UK
  1. adammarshall{at}

Gupta and Trautner suggest using nitrofurantoin as prophylaxis for recurrent urinary tract infections (UTIs) in non-pregnant women.1 They mention the risk of pulmonary toxicity (“nitrofurantoin lung”) associated with prolonged treatment but suggest that this occurs after years of treatment.

In Grampian we have identified 13 patients in the past four years with nitrofurantoin lung, 12 of whom …

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