Intended for healthcare professionals

Letters Bad medicine: the way we manage diabetes

European Medicines Agency must take account of cardiovascular harm associated with degludec insulin

BMJ 2013; 346 doi: (Published 11 June 2013) Cite this as: BMJ 2013;346:f3731
  1. Thomas A Schmidt, associate clinical research professor1,
  2. Clifford J Rosen, professor of medicine2,
  3. John S Yudkin, emeritus professor of medicine3
  1. 1Holbaek University Hospital, 4300 Holbaek, Denmark
  2. 2Maine Medical Center Research Institute, Scarborough, ME, USA
  3. 3University College London, London, UK
  1. tasm{at}

The way we manage diabetes is bad medicine and, with the increasing use of analogue insulin, type 2 diabetes is pharma’s lottery win.1 Degludec insulin (Tresiba), Novo Nordisk’s novel analogue, may be viewed in this context. Our concerns about its marketing led us to submit a letter to the European Medicines Agency (EMA) (available at:

The EMA approved degludec …

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