Intended for healthcare professionals

CCBYNC Open access
Research

Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f3706 (Published 27 June 2013) Cite this as: BMJ 2013;346:f3706

Re: Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies

A few questions arise as we go through the article:

1. The other confounding factors like Vit D consumption or exposure to sun-light have to be adjusted before reaching any conclusion. Only confounding of menopause has been taken care of.

2. PUFA gets converted into trans-fats after prolonged heating which is an oxidant and risk factor for cancer.

3. Compare the risk of breast cancer in various groups, like in India, Bengalies are fish eating community. Say,on globe also the breast cancer risk among Japanese should be compared with other countries. A comparison of breast cancer occurring in American and Japanese women reveals that both the incidence and mortality rates are markedly higher in the US(1).

References:

1. http://www.med.or.jp/english/journal/pdf/2009_01/039_044.pdf

Competing interests: No competing interests

04 July 2013
Neeru Gupta
Scientist E
Neeta Kumar, Jugal Kishore, KK Jani
Indian Council of Medical Research
Ansari Nagar, New Delhi-110029