Re: Diagnosis and management of recurrent urinary tract infections in non-pregnant women
Asymptomatic bacteruria occurs in about 1-2% of healthy adult women. Numerous studies have demonstrated that treatment of this does not reduce the incidence of symptomatic infection or pyleonephritis. In pregnancy the incidence of bacteruria is not significantly changed (1-2%)but it is associated with a 30% incidence of pyleonephritis, hence recommendations for screening and treating in pregnant women. The reasons for the greater incidence of sepsis are urinary stasis and loss of ureteric peristalsis and muscle tone associated with progestogens and immunosuppresion that occurs in pregnancy.
Competing interests: No competing interests