Intended for healthcare professionals

Clinical Review

Diagnosis and management of recurrent urinary tract infections in non-pregnant women

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f3140 (Published 29 May 2013) Cite this as: BMJ 2013;346:f3140

Re: Diagnosis and management of recurrent urinary tract infections in non-pregnant women

Asymptomatic bacteruria occurs in about 1-2% of healthy adult women. Numerous studies have demonstrated that treatment of this does not reduce the incidence of symptomatic infection or pyleonephritis. In pregnancy the incidence of bacteruria is not significantly changed (1-2%)but it is associated with a 30% incidence of pyleonephritis, hence recommendations for screening and treating in pregnant women. The reasons for the greater incidence of sepsis are urinary stasis and loss of ureteric peristalsis and muscle tone associated with progestogens and immunosuppresion that occurs in pregnancy.

Competing interests: No competing interests

01 June 2013
Andrew G Russell
Urologist
Rajesh Kavia
Northwick Park Hospital
Watford Road, Harrow HA1 3UJ