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Rapid response to:

Analysis

Restoring invisible and abandoned trials: a call for people to publish the findings

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f2865 (Published 13 June 2013) Cite this as: BMJ 2013;346:f2865

Rapid Response:

Re: Restoring invisible and abandoned trials: a call for people to publish the findings

Doshi and colleagues are concerned, understandably, at the use of control injections in vaccine trials, that are not true placebos. (1)

Perhaps there would be even more concern if people understood that such practices are not unusual, in vaccine trials.
The nature of any control injections, in vaccine trials, is sometimes difficult to ascertain, as Doshi and colleagues’ letter suggests.

In his chapter on vaccine safety, Moskowitz lists the sixteen vaccines that were mandated in the USA, in 2017. (2)
Four of the vaccines were subject to trials that used unspecified “placebos” as controls.
Five of the vaccines had no record of controlled safety studies.
Six of the vaccines were subject to trials where other vaccines were given as the control injections.
In the case of one vaccine, the control injection was a “placebo”, phenol 0.25%.

1 https://www.bmj.com/content/346/bmj.f2865/rr-7

2 Richard Moskowitz, MD, Vaccines, a reappraisal. Skyhorse Publishing, 2017. (pp34 et seq)

Competing interests: No competing interests

17 January 2019
Noel Thomas
retired/ part time GP
Bronygarn, Maesteg, Wales CF34 9AL