Intended for healthcare professionals

Rapid response to:

Analysis

Expect analgesic failure; pursue analgesic success

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f2690 (Published 03 May 2013) Cite this as: BMJ 2013;346:f2690

Rapid Response:

Re: Expect analgesic failure; pursue analgesic success

Your study shows that most of the effectiveness of taking medications comes from the placebo effect of taking the tablets and not from the active drug therein contained, for the harm almost certainly the opposite is the case.

This suggests that taking a placebo may be preferable for placebo responders.

The placebo responders can be found by their preference for taking placebos rather than active drugs, and the effectiveness of the placebos can be enhanced by the colour of the coating of the tablets as it has been shown for red coated analgesics, an empathetic approach of the practitioners, clear intuitive explanations and complicating the process of pill or potion taking.

Competing interests: No competing interests

10 June 2013
Adrian A Pierry
GP
freelance
Penarth CF64