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Letters Drug-grapefruit juice interactions

A more balanced approach to drug-grapefruit juice interactions

BMJ 2013; 346 doi: (Published 26 February 2013) Cite this as: BMJ 2013;346:f1073
  1. Warren D Backman, final year medical student1,
  2. Ameet Bakhai, consultant cardiologist2
  1. 1University College London, London WC1E 6BT, UK
  2. 2Barnet and Chase Farm Hospitals NHS Trust, Barnet EN5 3DJ, UK
  1. abakhai{at}

We question Pirmohamed’s focus on “severe, sometimes fatal, interactions” between grapefruit juice and drugs,1 which may bias BMJ readers and add to the excessive fear around grapefruit juice for patients and doctors alike.

Grapefruit juice is a rich source of flavonoids—antioxidants that have a preventive effect in many diseases. During more than 10 years …

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